The Relationship in Hypertensive Patients Endothelin Levels, Echocardiographic Findings and Valsartan

doi:10.4328/jcam.1518

April 23, 2014The Annals of Clinical and Analytical Medicine

The Relationship in Hypertensive Patients Endothelin Levels, Echocardiographic Findings and Valsartan

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Why the study?

Does valsartan reduce serum endothelin levels and left ventricular hypertrophy in hypertensive patients?

Structured PICO

Does valsartan reduce serum endothelin levels and left ventricular hypertrophy in hypertensive patients?

P

Population

23 patients (14 men, 9 women) with an age range of 33-70 years having Stage 1 (n=3) or Stage II (n=20) hypertension according to the criteria defined by the Joint National Committee Report VII (JNC VII).

I

Intervention

Valsartan

C

Comparator

Healthy controls

O

Outcome

Serum endothelin (ET) levels and left ventricular hypertrophy (LVH)surrogate

Hypertensive patients have higher serum endothelin levels compared to healthy controls, though the full effect of valsartan on these levels remains unclear due to incomplete data.

Implication

Higher endothelin in hypertension supports biomarker research; leaves open valsartan's effects on levels and LVH.

Discussion

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Cite This Study

A 2014 study studied this question.

synapsesocial.com/papers/6a7cf76b1a3e19cd44ec232f https://doi.org/10.4328/jcam.1518

View Full Paper

Ask AI

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The Relationship in Hypertensive Patients Endothelin Levels, Echocardiographic Findings and Valsartan

Structured PICO

Implication

Discussion

Cite This Study

The Relationship in Hypertensive Patients Endothelin Levels, Echocardiographic Findings and Valsartan

Structured PICO

Implication

Discussion

Cite This Study

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