Why the study?
Some post-AMI patients with left ventricular thrombus do not undergo coronary revascularization due to contraindications or patient preference, but outcomes comparing revascularization versus no revascularization in this population remain unclear.
Does coronary revascularization improve left ventricular thrombus resolution and reduce mortality in post-acute myocardial infarction patients?
Does coronary revascularization improve left ventricular thrombus resolution and reduce mortality in post-acute myocardial infarction patients?
In post-AMI patients with left ventricular thrombus, lack of coronary revascularization is associated with higher mortality, while optimal medical therapy (at least dual antithrombotic therapy) drives thrombus resolution.
May support individualized revascularization decisions in post-AMI LVT; leaves open causal benefits for prospective confirmation.
Background: The incidence of left ventricular thrombus (LVT), a significant complication postacute myocardial infarction (AMI), has seen a decline in the percutaneous coronary intervention era. Patients may not undergo coronary revascularization due to medical contraindications or patient preference. Objectives: This study compared post-AMI LVT patients treated with or without revascularization. Methods: This was a retrospective study of 263 consecutive post-AMI patients diagnosed with LVT from November 2012 to January 2021, retrieved from an echocardiography database. Patients were stratified by their revascularization status. Results: < .001) were associated with higher mortality after adjusting for age, sex, anemia, anterior AMI, and ejection fraction. Conclusion: Lack of revascularization in post-AMI LVT patients was associated with higher mortality but not LVT resolution. Optimizing medical therapy remains a key treatment goal.
No takes yet. Share an insight, caveat, or question.
Leow et al. (2025) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: