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July 13, 2020Acta Anaesthesiologica ScandinavicaOpen Access

Common clinical thresholds of intraoperative hypotension and 30‐day mortality following surgery: A retrospective cohort study

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Why the study?

Whether common intraoperative hypotension thresholds (SBP <80 mmHg, MAP <60 mmHg, and ΔSBP >20%) validly signal an increased risk of 30-day post-operative mortality is unclear.

Are common thresholds of intraoperative hypotension (SBP <80 mmHg, MAP <60 mmHg, ΔSBP >20%) associated with increased 30-day mortality following surgery?

Population

11 304 surgical patients

Comparison

Common intraoperative hypotension thresholds (SBP <80 mmHg, MAP <60 mmHg, and ΔSBP >20%)

Design

Retrospective registry-based cohort study

Follow-up

30 days

Authors

PDPhilippe DonyGrand Charleroi HospitalLSLaurence SeidelUniversity of LiègeGHGuy HallerUniversité Claude Bernard Lyon 1

Discussion

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Implication

SBP <80 mmHg and MAP <60 mmHg were associated with 30-day mortality; leaves open whether targeting these thresholds improves outcomes.

Structured PICO

Are common thresholds of intraoperative hypotension (SBP <80 mmHg, MAP <60 mmHg, ΔSBP >20%) associated with increased 30-day mortality following surgery?

P
Population
11,304 patients undergoing surgery between January 2015 and July 2016
I
Intervention
Intraoperative hypotension defined by systolic blood pressure (SBP) <80 mmHg, mean arterial pressure (MAP) <60 mmHg, or SBP percent drop from baseline (ΔSBP) >20%
C
Comparator
Patients without intraoperative hypotension reaching these thresholds
O
Outcome
30-day post-operative mortalityhard clinical

Commonly accepted thresholds of intraoperative hypotension (SBP < 80 mmHg and MAP < 60 mmHg) are valid alarming limits independently associated with increased 30-day post-operative mortality.

Cite This Study

Dony et al. (2020) studied this question.

synapsesocial.com/papers/6a7cf9223e89d9be1fec23b8https://doi.org/10.1111/aas.13670
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Also Consider

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  1. 1Intraoperative Blood Pressure What Patterns Identify Patients at Risk for Postoperative Complications?1990 · 138 citations
  2. 2Concurrence of Intraoperative Hypotension, Low Minimum Alveolar Concentration, and Low Bispectral Index Is Associated with Postoperative Death2015 · 83 citations
  3. 3Anesthetic Management and One-Year Mortality After Noncardiac Surgery2004 · 903 citations
  4. 4Complications and mortality in older surgical patients in Australia and New Zealand (the REASON study): a multicentre, prospective, observational study*2010 · 201 citations
  5. 5CARDIAC RISK FACTORS AND COMPLICATIONS IN NON-CARDIAC SURGERY1978 · 384 citations