Why the study?
Does flecainide cause wide complex tachycardia during stress testing?
Does flecainide cause wide complex tachycardia during stress testing?
Flecainide can have proarrhythmic effects, such as inducing wide complex tachycardia with 1:1 ventricular conduction during exercise testing, which can be difficult to differentiate on an electrocardiogram.
May signal flecainide proarrhythmia during exercise; single case leaves open need for routine stress testing.
Wide complex tachycardias may represent a rare proarrhythmic effect of some antiarrhythmic agents. The authors describe a patient who developed a wide complex tachycardia developing during stress testing while on therapy with flecainide, and the difficulty in interpreting the electrocardiogram. This article reviews potential proarrhythmic effects of flecainide in the treatment of atrial dysrhythmias and the difficulty in differentiating associated wide complex tachycardias.
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Randazzo et al. (1994) studied this question.
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