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January 3, 2024Open Access

Efficacy of Saccharomyces Cerevisiae Fermentation Product and Probiotic Supplementation on Growth Performance, Gut Microbiome and Immunity of Broiler Chickens

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Authors

SSS. SorenGMGuru Prasad MandalSMSamiran Mondal

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Overview

Randomized trial reveals improved feed efficiency, enhanced immunity, and reduced pathogens in broilers fed yeast fermentation product or probiotics, suggesting viable alternatives to antibiotics.

Key Points

  • To evaluate the efficacy of dietary supplementation with a probiotic (Bacillus subtilis) and a yeast postbiotic (Saccharomyces cerevisiae fermentation product) on broiler growth, gut health, and immunity as alternatives to in-feed antibiotics.
  • A total of 324 day-old Ven Cobb 400 chicks were randomly assigned to three dietary regimens (12 replicate pens of 9 chicks each): basal control diet (T1), basal diet plus Bacillus subtilis at 200 g/MT (T2), and basal diet plus Saccharomyces cerevisiae fermentation product (SCFP) at 1.25 kg/MT (T3).
  • Birds were evaluated for growth performance across 42 days; blood biochemistries, gut morphology, pathogen loads, and antibody titers were assessed at days 28, 35, and 42.
  • SCFP supplementation (T3) significantly improved overall feed conversion ratio (1–42 days) compared to control (P<0.05), while significantly lowering blood cholesterol and corticosterone concentrations versus T1 and T2 (P<0.05).
  • Both SCFP and probiotic treatments significantly decreased total E. coli, Salmonella, and ESBL-producing Enterobacteriaceae counts, while significantly increasing intestinal villus height and villus-to-crypt depth ratio relative to control (P<0.05).
  • Supplementation with either SCFP or probiotics significantly enhanced antibody titers against Newcastle disease and Infectious bursal disease viruses on day 28 (P<0.05).

Cite This Study

Soren et al. (2024) studied this question.

synapsesocial.com/papers/6a7cfaf89092f18ef00eb5e2https://doi.org/10.20944/preprints202401.0277.v1
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Efficacy of Saccharomyces cerevisiae Fermentation Product and Probiotic Supplementation on Growth Performance, Gut Microflora and Immunity of Broiler Chickens2024 · 37 citations
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  3. 3Evaluation of using probiotics, prebiotics and symbiotic as growth promoters in broilers and their effects on some growth performance-related genes2024 · 4 citations
  4. 4Nutraceuticals vs. antibiotic growth promoters: differential impacts on performance, meat quality, blood lipids, cecal microbiota, and organ histomorphology of broiler chicken2024 · 13 citations
  5. 5Evaluating the efficacy of Lactobacillus acidophilus derived Postbiotics on Growth metrics, Health, and Gut Integrity in Broiler Chickens2024