Why the study?
Does aspirin 325 mg/d improve saphenous vein graft or IMA graft patency between 1 and 3 years after CABG in patients who received aspirin for 1 year post-CABG?
Population
Patients 1 year post-CABG who received aspirin 325 mg/d for 1 year and underwent 1-year postoperative…
Comparison
Aspirin 325 mg/d for 2 additional years. vs Placebo for 2 additional years.
Design
RCT, randomized
Follow-up
2 years (between 1 and 3 years post-CABG)
Authors
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Does not support continuing aspirin beyond 1 year for graft patency after CABG; challenges extended use and informs optimal-duration trials.
Does aspirin 325 mg/d improve saphenous vein graft or IMA graft patency between 1 and 3 years after CABG in patients who received aspirin for 1 year post-CABG?
Continuing aspirin beyond 1 year after CABG does not significantly improve saphenous vein or IMA graft patency at 3 years compared to placebo.
Goldman et al. (1994) studied this question.
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