Why the study?
Does the isotype-specific antibody response differ between cattle that eliminate FMDV and those that become carriers?
Population
Vaccinated and susceptible cattle challenged with foot-and-mouth disease virus (FMDV)
Comparison
Challenge with FMDV by direct contact or… vs Comparison between cattle that eliminated FMDV…
Design
Preclinical
Follow-up
5 weeks
Authors
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May identify FMDV carriers via secretory IgA in cattle; leaves open diagnostic utility pending validation.
Does the isotype-specific antibody response differ between cattle that eliminate FMDV and those that become carriers?
FMDV-specific IgA responses in mucosal secretions and serum could serve as a basis to differentiate vaccinated or recovered cattle from FMDV carriers.
Salt et al. (1996) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: