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April 1, 1999Antimicrobial Agents and ChemotherapyOpen Access

Impact ofgyrAandparCMutations on Quinolone Resistance, Doubling Time, and Supercoiling Degree ofEscherichia coli

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SBSimone BagelFederal Office for Information SecurityVHVolker HüllenBWB. WiedemannGoethe University Frankfurt

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Bagel et al. (1999) studied this question.

synapsesocial.com/papers/6a7cfe4a3e89d9be1fec2525https://doi.org/10.1128/aac.43.4.868
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1DNA Gyrase: Structure and Function1991 · 735 citations
  2. 2DNA supercoiling in <i>Escherichia coli: topA</i> mutations can be suppressed by DNA amplifications involving the <i>tolC</i> locus1989 · 63 citations
  3. 3An Escherichia coli DNA topoisomerase I mutant has a compensatory mutation that alters two residues between functional domains of the DNA gyrase A protein1992 · 14 citations
  4. 4Mechanisms of Bacterial Resistance to Quinolones.1996 · 50 citations
  5. 5The local repressor AcrR plays a modulating role in the regulation of <i>acrAB genes of Escherichia coli</i> by global stress signals1996 · 401 citations