May 31, 2011The British Journal of PsychiatryOpen Access

Revascularisation and mortality rates following acute coronary syndromes in people with severe mental illness: comparative meta-analysis

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Why the study?

Does severe mental illness reduce the receipt of invasive coronary procedures and increase mortality in patients following acute coronary syndromes?

Population

825,754 individuals following acute coronary syndromes, comparing those with defined mental disorders to…

Comparison

Diagnosis of severe mental illness or… vs Individuals without mental ill health

Design

Meta-analysis

Follow-up

up to 1 year

Authors

AMAlex J. MitchellOregon National Primate Research Center DLDavid LawrenceCurtin University

Discussion

Member takes

Implication

Requires addressing care inequities in ACS patients with mental disorders; confirms lower procedure rates and higher 1-year mortality.

Structured PICO

Does severe mental illness reduce the receipt of invasive coronary procedures and increase mortality in patients following acute coronary syndromes?

Population

825,754 individuals following acute coronary syndromes (myocardial infarction and unstable angina), comparing those with defined mental disorders (including a subgroup with schizophrenia or related psychosis) to those without mental ill health. All included studies following acute coronary syndrome originated in the USA.

Intervention

Diagnosis of severe mental illness or schizophrenia (exposure)

Comparator

Individuals without mental ill health

Outcome

Receipt of invasive coronary procedures (revascularisation, angiography, angioplasty, and coronary artery bypass grafting) and mortality up to 1 year following acute coronary syndromehard clinical

Patients with severe mental illness experience significant disparities in cardiovascular care following acute coronary syndromes, receiving fewer invasive revascularization procedures and suffering higher 1-year mortality.

Limitations

All studies following acute coronary syndrome originated in the USA, which may not be representative of all healthcare systems
The definition of severe mental illness varied across some studies
All studies were retrospective and none distinguished current from historical mental ill health
Poor data quality regarding hospitalisation and patient-provider factors underlying poor outcomes

Cite This Study

Mitchell et al. (2011) studied this question.

synapsesocial.com/papers/6a7d0550d685fe2c2d7751a1 https://doi.org/10.1192/bjp.bp.109.076950

View Full Paper

Ask AI

Bookmark

Revascularisation and mortality rates following acute coronary syndromes in people with severe mental illness: comparative meta-analysis

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Revascularisation and mortality rates following acute coronary syndromes in people with severe mental illness: comparative meta-analysis

Discussion

Member takes

Implication

Structured PICO

Limitations

Cite This Study

Also Consider

Also Consider