Why the study?
Does oral quinidine suppress recurrent electrical storms in a patient with Brugada syndrome?
Does oral quinidine suppress recurrent electrical storms in a patient with Brugada syndrome?
Oral quinidine can be an effective therapy for suppressing malignant electrical storms in patients with Brugada syndrome.
Hypothesis-generating for quinidine in Brugada storm; prospective trials needed before clinical adoption.
Brugada syndrome is an inherited form of arrythmogenic disease associated with a coved-type ST segment elevation in right precordial leads and an increased risk of sudden cardiac death due to ventricular fibrillation (VF) in young, otherwise healthy adults. Electrical storm is malignant but rare in patients with Brugada syndrome. This is the case of a patient who was diagnosed with Brugada syndrome with repetitive discharges of implantable cardioverter-defibrillator during episodes of ventricular tachycardia/VF. The patient was given oral quinidine, which successfully suppressed the recurrence of electrical storms. KEYWORDS Brugada syndrome, bangungut, quinidine.
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Go-Sumalpong et al. (2014) studied this question.
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