Why the study?
Does the Lymph3Cx assay accurately distinguish PMBCL from DLBCL subtypes using formalin-fixed, paraffin-embedded tissue?
Does the Lymph3Cx assay accurately distinguish PMBCL from DLBCL subtypes using formalin-fixed, paraffin-embedded tissue?
The Lymph3Cx assay provides a robust and reproducible method for distinguishing PMBCL from DLBCL using routinely available formalin-fixed, paraffin-embedded tissue.
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May enable reliable PMBCL subtyping on FFPE tissue; leaves open prospective validation before clinical adoption.
Mottok et al. (2018) studied this question.
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