Nuclear Translocation of the N-terminal Prodomain of Interleukin-16

View Full Paper

Ask AI

Bookmark

Population

In vitro cell model

Design

Preclinical

Authors

Discussion

May influence immune cell proliferation in cardiac inflammation; leaves open its role in cardiovascular disease models.

Population

In vitro cell model

Intervention

Nuclear targeting of the IL-16 N-terminal prodomain

Outcome

Nuclear translocation and effect on cell cycle progression

The N-terminal prodomain of pro-IL-16 functions as an active protein that translocates to the nucleus and induces G0/G1 cell cycle arrest.

Zhang et al. (2001) studied this question.

View Full Paper

Ask AI

Bookmark