June 12, 2008Journal of Cardiovascular Electrophysiology

Effect of Radiofrequency Ablation of Atrial Flutter on the Natural History of Subsequent Atrial Arrhythmias

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Why the study?

Does radiofrequency ablation of atrial flutter prevent the subsequent development of atrial fibrillation in patients without previous atrial fibrillation?

Population

196 patients with atrial flutter as the sole atrial arrhythmia and no previous atrial fibrillation…

Comparison

Radiofrequency ablation of atrial flutter vs Medical therapy only

Design

Cohort

Follow-up

5 years

Authors

DLDavid LuriaHebrew University of Jerusalem DHDavid O. HodgeGeneral Cardiology KMKristi H. MonahanElectrophysiology

Discussion

Member takes

Implication

Ablation of atrial flutter was not associated with lower AF rates; leaves open whether substrate modification alters AF progression in observational data.

Structured PICO

Does radiofrequency ablation of atrial flutter prevent the subsequent development of atrial fibrillation in patients without previous atrial fibrillation?

Population

196 patients with atrial flutter (AFL) as the sole atrial arrhythmia and no previous atrial fibrillation (AF), including 137 patients who underwent successful AFL ablation at Mayo Clinic between 1997 and 2003 (50 with structural heart disease, 87 without) and 59 control patients.

Intervention

Radiofrequency ablation of atrial flutter

Comparator

Medical therapy only (control group of 59 patients with AFL and no history of paroxysmal AF)

Outcome

Occurrence of atrial fibrillation (symptomatic, paroxysmal, and chronic) after AFL ablationhard clinical

Successful radiofrequency ablation of atrial flutter does not prevent the subsequent development of atrial fibrillation compared to medical therapy alone, suggesting AF progression continues independent of the AFL substrate.

Cite This Study

Luria et al. (2008) studied this question.

synapsesocial.com/papers/6a7d1134469c795fc4278ac1 https://doi.org/10.1111/j.1540-8167.2008.01206.x

Topics

Atrial fibrillation Persistent AF management AF ablation outcomes Anticoagulation in AF

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Implication

Ablation of atrial flutter was not associated with lower AF rates; leaves open whether substrate modification alters AF progression in observational data.

Effect of Radiofrequency Ablation of Atrial Flutter on the Natural History of Subsequent Atrial Arrhythmias

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Effect of Radiofrequency Ablation of Atrial Flutter on the Natural History of Subsequent Atrial Arrhythmias

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider