Why the study?
Does dietary astaxanthin reduce oxidative stress and improve vascular histopathology in spontaneously hypertensive rats?
Population
Spontaneously hypertensive rats (SHR)
Comparison
Oral administration of dietary astaxanthin (ASX-O) vs Control vehicle and olive oil
Design
Preclinical
Authors
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Supports astaxanthin antioxidant effects in hypertensive rats; leaves open translation to human hypertension therapy.
Does dietary astaxanthin reduce oxidative stress and improve vascular histopathology in spontaneously hypertensive rats?
Dietary astaxanthin demonstrates antioxidant properties and favorable vascular histopathological effects in a rat model of hypertension.
Hussein et al. (2006) studied this question.
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