Why the study?
Can ECG-gated multidetector-row computed tomography be used to assess left ventricular function in patients with suspected coronary artery disease?
Can ECG-gated multidetector-row computed tomography be used to assess left ventricular function in patients with suspected coronary artery disease?
ECG-gated multidetector-row computed tomography is a viable modality for the combined noninvasive assessment of coronary anatomy and left ventricular function.
Should not yet change practice in suspected CAD; leaves open prospective validation of MDCT against reference standards.
An accurate quantitative and qualitative assessment of cardiac function is critical for clinical diagnosis, risk stratification, management and prognosis in patients with suspected or documented heart disease. Magnetic resonance thanks to its excellent temporal and spatial resolution is currently considered a reference standard in the assessment of cardiac function. Multidetector-row computed tomographic scanners, with sub-second rotation times and dedicated cardiac reconstruction algorithms, have shown their ability to acquire high-resolution images suitable for coronary imaging. With retrospective ECG- gating technique, diastolic and systolic images can be produced and analyzed to assess left ventricle functional parameters. The combination of noninvasive coronary artery imaging and assessment of cardiac function with multidetector-row computed tomography is a suitable approach to a conclusive cardiac work-up in patients with suspected coronary artery disease.
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Rengo et al. (2009) studied this question.
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