Why the study?
The study investigated short-term and long-term outcomes to identify whether an invasive PCI strategy or a conservative strategy is more beneficial in NSTEMI patients older than 80 years.
Does an invasive strategy with PCI reduce all-cause death in NSTEMI patients older than 80 years compared to a conservative strategy?
Does an invasive strategy with PCI reduce all-cause death in NSTEMI patients older than 80 years compared to a conservative strategy?
In NSTEMI patients older than 80 years, an invasive PCI strategy is associated with significantly lower short-term all-cause mortality compared to conservative management.
Invasive PCI was associated with better outcomes in selected NSTEMI patients >80 years; leaves open whether routine use improves survival in broader populations.
Aims/Background The present study investigated the short-term and long-term outcomes of an invasive strategy in percutaneous coronary intervention (PCI) and a conservative strategy in non-ST-segment elevation myocardial infarction (NSTEMI) patients older than 80 years, with the aim to identify the strategy that is more beneficial than the other to this demographic population. Methods A total of 139 patients from Beijing Anzhen Hospital and the Cao County People’s Hospital were included in this study, comprising those aged >80 years and diagnosed with NSTEMI between 2017 and 2022. The main observation indicator was all-cause death, whereas the secondary indicators included composite endpoint events of recurrent myocardial infarction, need for urgent revascularization, recurrent angina, stroke, death, and major bleeding. Results Among these participants, 72 patients received PCI while the rest (n = 67) received the conservative treatment. Compared to patients who received the conservative treatment, patients who received PCI had significantly lower rates of all-cause mortality during hospitalization and 30 days of follow-up. Conclusion Our findings support that patients older than 80 years with NSTEMI can benefit from PCI compared to the conservative treatment.
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Li et al. (2024) studied this question.
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