Why the study?
Activation mapping guided catheter ablation of VAs is limited when relying only on bipolar EGMs, and combining bipolar and unipolar EGMs was hypothesized to better identify focal VA origin and reduce recurrence.
Does activation mapping with combined unipolar and bipolar electrograms reduce the recurrence rate in patients undergoing repeat ablation for idiopathic ventricular arrhythmias?
Does activation mapping with combined unipolar and bipolar electrograms reduce the recurrence rate in patients undergoing repeat ablation for idiopathic ventricular arrhythmias?
The use of combined unipolar and bipolar electrograms during catheter ablation for idiopathic ventricular arrhythmias improves the identification of earliest activation sites and is associated with lower long-term recurrence rates compared to bipolar mapping alone.
INTRODUCTION: Activation mapping guided catheter ablation (CA) of ventricular arrhythmias (VAs) is limited in some cases when it is only relied on bipolar electrogram (EGM). We hypothesized that activation mapping with use of combined bipolar and unipolar EGM facilitates to identify the focal origin of VAs and results in reduction of recurrence rate of CA of VAs. METHODS: We analyzed the data of patients undergoing repeat ablations for idiopathic out-flow tract VAs. The EGM of the 1 st and 2 nd ablations were compared for earliest local activation time (LAT), presence of discrete potentials, and polarity reversal, unipolar potential morphology (QS or non-QS), potential amplitude and activation slope. RESULTS: Thirty-seven patients were included. The Local activation time was significantly earlier in the 2nd ablation as compared to the 1st procedure (36.90 msec vs 31.85 msec, P < 0.01). The incidence of discrete potentials and polarity reversal were similar in both procedures (51% vs 57%, P = 0.8 and 62% in both the occasions, respectively). The unipolar voltage was similar in both occasions (6.94 mV vs 7.22 mV in repeat ablations, P = 0.7). The recurrence rate (5.7%) was significantly lower with routine use of combined unipolar and bipolar EGMs, as compared to the use of bipolar EGM alone (16.7%) CONCLUSIONS: Use of both bipolar and unipolar electrograms helps in better delineation of the sites of earliest activation for effective ablation of VAs. Use of unipolar electrograms in addition to bipolar electrograms is associated with lower long term recurrence rate.
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Jena et al. (2021) studied this question.
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