Why the study?
Does surgical margin width affect recurrence and survival in patients with low grade central osteosarcoma?
Population
20 patients with low grade central osteosarcoma, age range 15-83 years, all tumors arising in the lower limb.
Comparison
Surgery (intralesional vs wide/radical margins) vs Intralesional surgery vs radical margins
Design
Cohort
Follow-up
16 [2.5-48] years
Authors
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Supports wide margins to limit recurrence in low-grade central osteosarcoma; leaves open prospective validation of margin strategies.
Does surgical margin width affect recurrence and survival in patients with low grade central osteosarcoma?
Low grade central osteosarcoma is controllable by surgery alone if at least wide margins are used, yielding high long-term survival.
Choong et al. (1996) studied this question.
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