Why the study?
No immunohistochemical study had reported the pattern of myocardial cTnI egression in a minimally invasive myocardial infarction model.
Does a minimally invasive myocardial infarction model in dogs cause egression of cTnI from non-necrotic myocardium?
Does a minimally invasive myocardial infarction model in dogs cause egression of cTnI from non-necrotic myocardium?
In a canine minimally invasive MI model, cTnI egression occurs in both necrotic and specific non-necrotic myocardial regions, providing insight into biomarker release mechanisms.
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Provides minimally invasive canine MI model for cTnI mapping; leaves open translation to human diagnostics.
Mikrani et al. (2019) studied this question.
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