Key result
Gastric dilatation-volvulus and blunt chest trauma were associated with significantly higher cTnI levels compared to healthy controls (P<0.001), with increased troponins in 93% and 75% of dogs, respectively.
Why the study?
Can human assays for cardiac troponins accurately detect acute myocardial damage in dogs with gastric dilatation-volvulus or blunt chest trauma?
Population
92 dogs, including 56 healthy controls, 28 at risk for acute myocardial damage due to gastric…
Comparison
Measurement of cardiac troponin T and myoglobin… vs Healthy control dogs (n=56).
Design
Preclinical
Follow-up
48 hours (for GDV dogs)
Authors
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Human cTnI assays may aid myocardial injury detection in canine GDV or trauma; leaves open prospective validation before clinical adoption.
Observational (n=92)
Can human assays for cardiac troponins accurately detect acute myocardial damage in dogs with gastric dilatation-volvulus or blunt chest trauma?
p-value: p=<.001
Human assays for cardiac troponins are applicable for canine use and effectively detect acute myocardial damage in dogs suffering from gastric dilatation-volvulus or blunt chest trauma.
Burgener et al. (2006) conducted an observational in Gastric dilatation-volvulus and blunt chest trauma (n=92). Gastric dilatation-volvulus and blunt chest trauma vs. Healthy dogs was evaluated on Cardiac troponin I (cTnI) and T (cTnT) levels at presentation (p=<.001). Gastric dilatation-volvulus and blunt chest trauma were associated with significantly higher cTnI levels compared to healthy controls (P<0.001), with increased troponins in 93% and 75% of dogs, respectively.
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