Key result
Gastric dilatation-volvulus and blunt chest trauma were associated with significantly higher levels of cTnI, CK-MB, myoglobin, and lactic acid compared to healthy control dogs (P<0.001).
Why the study?
Can point-of-care and automated systems accurately measure cardiac troponins to detect acute myocardial damage in dogs with GDV or BCT?
Population
92 dogs, including 56 healthy controls, 28 with gastric dilatation-volvulus, and 8 with blunt chest trauma.
Comparison
Measurement of cardiac biomarkers. vs Healthy control dogs.
Design
Preclinical
Follow-up
48 hours (for GDV dogs)
Authors
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Elevated troponins may signal myocardial injury in canine GDV or BCT; leaves open whether assays guide prognosis or therapy.
Observational (n=92)
Can point-of-care and automated systems accurately measure cardiac troponins to detect acute myocardial damage in dogs with GDV or BCT?
p-value: p=<0.001
Human point-of-care and automated systems can successfully measure canine cardiac troponins, revealing a high incidence of myocardial damage in dogs with gastric dilatation-volvulus and blunt chest trauma.
Burgener et al. (2006) conducted an observational in Acute myocardial damage (n=92). Gastric dilatation-volvulus and blunt chest trauma vs. Healthy dogs was evaluated on cTnI, CK-MB, myoglobin, and lactic acid levels at presentation (p=<0.001). Gastric dilatation-volvulus and blunt chest trauma were associated with significantly higher levels of cTnI, CK-MB, myoglobin, and lactic acid compared to healthy control dogs (P<0.001).
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