Why the study?
Does prehypertension increase the risk of coronary heart disease compared to optimal blood pressure in Asian and Western populations?
Population
591,664 participants from 17 prospective cohort studies, including Asian and Western populations
Comparison
Prehypertension vs Optimal blood pressure (<120/80 mm Hg)
Design
Meta-analysis
Authors
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Prehypertension signals elevated CHD risk warranting attention; extends prior evidence by quantifying stronger Western vs Asian associations.
Does prehypertension increase the risk of coronary heart disease compared to optimal blood pressure in Asian and Western populations?
Prehypertension is associated with a significantly increased risk of coronary heart disease, with a more pronounced effect and higher population-attributable risk in Western compared to Asian populations.
Cai et al. (2015) studied this question.