Why the study?
Is plaque eccentricity associated with advanced plaque morphology and components in the superficial femoral artery of patients with an ankle-brachial index < 1.00?
Is plaque eccentricity associated with advanced plaque morphology and components in the superficial femoral artery of patients with an ankle-brachial index < 1.00?
In the superficial femoral artery, plaque eccentricity is associated with advanced atherosclerotic features including larger plaque burden, more lipid content, and increased calcification despite preserved lumen size.
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Eccentricity may flag advanced SFA plaques with higher calcification; hypothesis-generating for progression or outcomes in PAD.
Li et al. (2010) studied this question.
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