Why the study?
Does a maximal stress test inducing myocardial ischemia increase circulating endothelial progenitor cells in patients with coronary artery disease?
Population
39 subjects, including patients with coronary artery disease with or without exercise-induced myocardial…
Comparison
Maximal stress test resulting in… vs CAD patients without exercise-induced ischemia…
Design
Cohort
Follow-up
up to 144 hours
Authors
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Ischemia-specific EPC mobilization in CAD may reflect a physiological response; leaves open therapeutic implications pending prospective validation.
Does a maximal stress test inducing myocardial ischemia increase circulating endothelial progenitor cells in patients with coronary artery disease?
Exercise-induced myocardial ischemia triggers a significant, time-dependent increase in circulating endothelial progenitor cells and VEGF in patients with CAD, suggesting a physiological neovascularization response to transient ischemia.
Adams et al. (2004) studied this question.
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