Why the study?
Does oxidized low-density lipoprotein (Ox-LDL) accelerate adhesion and alter morphology in washed human blood platelets in vitro?
Does oxidized low-density lipoprotein (Ox-LDL) accelerate adhesion and alter morphology in washed human blood platelets in vitro?
Ox-LDL activates platelets and accelerates their adhesion in vitro, suggesting a mechanism by which it may contribute to pathological thrombosis and arteriosclerosis.
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Ox-LDL may promote thrombosis; extends in vitro mechanistic data but leaves open clinical translation to arteriosclerosis.
Zhao et al. (1995) studied this question.
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