Why the study?
Is the number of circulating endothelial progenitor cells reduced in patients with non-dipper essential hypertension compared to dippers?
Population
45 patients with newly identified essential hypertension, including 20 dippers and 25 non-dippers.
Comparison
Non-dipper hypertension vs Dipper hypertension
Design
Cross-sectional
Authors
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Non-dipper hypertension may signal impaired vascular repair; hypothesis-generating and requires prospective validation before clinical consideration.
Is the number of circulating endothelial progenitor cells reduced in patients with non-dipper essential hypertension compared to dippers?
Non-dipper hypertension is associated with a reduced number of circulating endothelial progenitor cells, suggesting impaired vascular repair capacity in this patient subgroup.
Kim et al. (2012) studied this question.
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