Key result
Non-dipper hypertensive patients exhibited smaller nocturnal decreases in cardiac index (-12.0% vs -17.5%) and stroke index (1.5% vs -2.2%) compared to dippers.
Why the study?
Do diurnal variations in systemic hemodynamic indices and baroreflex sensitivity differ between non-dipper and dipper hypertensive patients?
Population
45 subjects with essential hypertension, including 26 non-dippers and 19 dippers.
Design
Cross-sectional
Authors
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Suggests hemodynamic distinctions in non-dipping hypertension; hypothesis-generating and should not yet alter management.
Observational (n=45)
Do diurnal variations in systemic hemodynamic indices and baroreflex sensitivity differ between non-dipper and dipper hypertensive patients?
Absolute Event Rate: -12% vs -17.5%
Non-dipper essential hypertension is characterized by an inadequate nocturnal decrease in cardiac and stroke indices, suggesting relative volume expansion or malsuppressed sympathetic activity.
Takakuwa et al. (2001) conducted an observational in Essential hypertension (n=45). Non-dipper blood pressure pattern vs. Dipper blood pressure pattern was evaluated on Nocturnal decrease in cardiac index (%). Non-dipper hypertensive patients exhibited smaller nocturnal decreases in cardiac index (-12.0% vs -17.5%) and stroke index (1.5% vs -2.2%) compared to dippers.
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