Illuminating DNA: The assembly of two tailored nucleic acids (colored blue and brown in the scheme) in the presence of hemin yields a G-quadruplex that exhibits peroxidase-like activity and catalyzes the generation of chemiluminescence in the presence of H2O2 and luminol. The DNAzyme is employed for the analysis of DNA (green) in solution and on surfaces.
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Xiao et al. (2004) studied this question.
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