Why the study?
Saphenous vein grafts frequently fail due to intimal hyperplasia from arterial pressures, and the VEST external support device designed to mitigate this has been tested in few RCTs.
Does the VEST external support device mitigate intimal hyperplasia and SVG failure in patients undergoing CABG with saphenous vein grafts?
Does the VEST external support device mitigate intimal hyperplasia and SVG failure in patients undergoing CABG with saphenous vein grafts?
This review summarizes the randomized evidence on the VEST external support device for mitigating intimal hyperplasia in saphenous vein grafts during CABG.
VEST may reduce SVG intimal hyperplasia; leaves open effects on graft failure and clinical outcomes.
Saphenous vein grafts (SVGs) are the most frequently used conduits in coronary artery bypass grafting (CABG), but their higher rate of occlusion compared to arterial conduits remains a concern. Previous studies have shown that SVG failure is mainly driven by intimal hyperplasia, an adaptative response to higher pressures of the arterial circulation. The VESTTM device (Vascular Graft Solutions, Tel Aviv, Israel), an external support designed to mitigate intimal hyperplasia in SVGs, has been tested in few clinical trials (RCTs). Herein, we descriptively evaluated the randomized evidence on the VEST device.
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Soletti et al. (2023) studied this question.
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