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March 25, 2010Nucleic Acids ResearchOpen Access

Targeting of 5-aza-2′-deoxycytidine residues by chromatin-associated DNMT1 induces proteasomal degradation of the free enzyme

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KPKatan I. PatelEdinburgh Cancer ResearchJDJacqueline DicksonEdinburgh Cancer ResearchKMKenneth M. MacLeodUniversity of Exeter

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Patel et al. (2010) studied this question.

synapsesocial.com/papers/6a7d328ee6f633beba6e4eb9https://doi.org/10.1093/nar/gkq187
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Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Properties and localization of DNA methyltransferase in preimplantation mouse embryos: implications for genomic imprinting.1992 · 236 citations
  2. 2DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B2007 · 390 citations