What question did this study set out to answer?

To identify the specific laryngeal abnormalities responsible for persistent hoarseness in asthmatic patients using inhaled corticosteroid therapy.

November 1, 1983ThoraxOpen Access

Dysphonia caused by inhaled steroids: recognition of a characteristic laryngeal abnormality.

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To identify the specific laryngeal abnormalities responsible for persistent hoarseness in asthmatic patients using inhaled corticosteroid therapy.
Evaluated 14 asthmatic patients presenting with persistent dysphonia while using inhaled corticosteroids, including beclomethasone dipropionate, betamethasone valerate, or budesonide.
Followed a prospective cohort of 9 patients starting aerosol steroid therapy with monthly laryngeal examinations for one year.
Bilateral adductor vocal cord deformity with cord bowing on phonation occurred in 9 of 14 patients (64%), which resolved several weeks after discontinuing inhaled steroids.
Among the 5 patients without cord deformity, laryngeal candidiasis was the exclusive cause of dysphonia in 3 patients, while 2 cases were determined to be psychogenic.
In the prospective 1-year cohort (N=9), 3 patients developed vocal cord deformity, though only 1 exhibited persistent dysphonia.

Authors

AWAlexander WilliamsLincoln Medical Center MBM S Baghat DSD E StableforthHeartlands Hospital

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Implication

Observational study reveals bilateral vocal cord bowing causes dysphonia in asthmatics using inhaled steroids, suggesting a reversible local steroid myopathy.

Cite This Study

Williams et al. (1983) studied this question.

synapsesocial.com/papers/6a7d39a41e40f448689659b3 https://doi.org/10.1136/thx.38.11.813

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Implication

Observational study reveals bilateral vocal cord bowing causes dysphonia in asthmatics using inhaled steroids, suggesting a reversible local steroid myopathy.

Dysphonia caused by inhaled steroids: recognition of a characteristic laryngeal abnormality.

Key Points

Discussion

Implication

Cite This Study

Dysphonia caused by inhaled steroids: recognition of a characteristic laryngeal abnormality.

Key Points

Discussion

Implication

Cite This Study

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