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Atherothrombosis drives most ischaemic events and death; leaves open targeted therapies in observational data.
oronary atherosclerosis is the underlying cause of nearly all cases of ischaemic heart disease, and superimposed thrombosis is the cause of the great majority of acute coronary syndromes. 1 2 The pathogenesis of peripheral arterial disease and, to a great extent, ischaemic stroke is similar. Thus, "atherothrombosis" is the leading cause of severe disability and cardiovascular death. . . . . . . . . . .
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Erling Falk (2003) studied this question.
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