Why the study?
Does varying calcium and magnesium concentrations in the carotid sinus perfusate alter the systemic blood pressure response threshold and sensitivity in cats?
Population
Cats (isolated carotid sinus model)
Comparison
Variations in calcium and magnesium… vs Control perfusate with 1.1 mM calcium
Design
Preclinical
Authors
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Calcium modulates baroreceptor threshold in cats; leaves open any human relevance for hypertension or reflex therapies.
Does varying calcium and magnesium concentrations in the carotid sinus perfusate alter the systemic blood pressure response threshold and sensitivity in cats?
Increasing calcium concentration in the carotid sinus perfusate increases the threshold for the baroreceptor reflex blood pressure response in cats, while decreasing calcium lowers the threshold.
Diana L. Kunze (1979) studied this question.
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