Independent association of left atrial function with exercise capacity in patients with preserved ejection fraction
Population
486 patients with preserved left ventricular ejection fraction and negative exercise echocardiography for…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
LA strain may refine exercise capacity assessment in preserved LVEF; hypothesis-generating and requires prospective validation before practice change.
Structured PICO
P
Population
486 patients with preserved left ventricular ejection fraction (LVEF) and negative exercise echocardiography for ischaemia
O
Outcome
Exercise capacity (estimated metabolic equivalents [METs] and per cent predicted METs) and left ventricular filling pressure (E/e') response to exercisesurrogate
In patients with preserved LVEF, reduced left atrial function measured by speckle tracking echocardiography is independently associated with impaired exercise capacity, highlighting the importance of ventriculo-atrial coupling.
Cite This Study
Kusunose et al. (2012) studied this question.