Why the study?
Exercise intolerance is the leading manifestation of HFpEF or HFmrEF, and LA function might modulate LV filling and pulmonary venous pressures, but its association with maximal exercise capacity needed assessment.
Does impaired left atrial reservoir strain predict reduced maximal exercise capacity in patients with HFpEF or HFmrEF?
Comparison
Peak VO2 < 14 mL/kg/min vs peak VO2 ≥ 14 mL/kg/min
Design
Prospective registry-based observational study
Authors
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Supports LA reservoir strain for identifying low exercise capacity in HFpEF/HFmrEF; leaves open prospective validation before clinical use.
Does impaired left atrial reservoir strain predict reduced maximal exercise capacity in patients with HFpEF or HFmrEF?
In patients with HFpEF or HFmrEF, reduced left atrial reservoir strain is a strong independent predictor of severely impaired exercise capacity.
Maffeis et al. (2020) studied this question.