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February 1, 1964CirculationOpen Access

Aneurysms of the Thoracic Aorta

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Why the study?

What is the natural history and prognosis of untreated thoracic aortic aneurysms?

Population

107 patients with a clinical diagnosis of aneurysm of the thoracic aorta made at the Mayo Clinic between…

Design

Cohort

Authors

JJJohn W. JoyceMayo ClinicJFJohn F. FairbairnInstitute for Cardiovascular Diseases of VojvodinaOKOwings W. KincaidMayo Clinic

Discussion

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Overview

Emphasizes high rupture and CVD mortality in untreated thoracic aortic aneurysms; leaves open contemporary natural history with surveillance.

Structured PICO

What is the natural history and prognosis of untreated thoracic aortic aneurysms?

P
Population
107 patients with a clinical diagnosis of aneurysm of the thoracic aorta made at the Mayo Clinic between 1945 and 1955, average age 59.3 years, male to female ratio 2.8:1.
I
Intervention
None (observational study of untreated natural history)
O
Outcome
Survival and cause of deathhard clinical

This historical cohort study demonstrates that untreated thoracic aortic aneurysms carry a poor prognosis, with death frequently resulting from rupture or associated cardiovascular disease, providing a baseline for evaluating surgical treatments.

Cite This Study

Joyce et al. (1964) studied this question.

synapsesocial.com/papers/6a7d46aee9ddcd9870aa17e2https://doi.org/10.1161/01.cir.29.2.176
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Thoracoabdominal Aortic Aneurysms: Experience with 372 Patients1994 · 87 citations
  2. 2Clinical Features and Prognosis in Dissecting Aneurysm of the Aorta1967 · 208 citations
  3. 3High Frequency of Thoracic Aneurysms in Patients with Abdominal Aortic Aneurysms2010 · 70 citations
  4. 4Diagnostic and surgical management of patients with aneurysms of the thoracic aorta with various causes. Echocardiography and contrast enhanced computed tomography in prophylactic replacement of the ascending aorta.1986 · 7 citations
  5. 5Prognostic Impact of Pulmonary Diseases in 952 Patients with Thoracic and/or Abdominal Aortic Aneurysm2024