Why the study?
Although chronic obstructive pulmonary disease and lung cancer are common in patients with TAA and AAA, the prevalence of these and other pulmonary diseases regarding their relation to aortic aneurysm outcomes was undetermined.
What is the prognostic impact of coexisting pulmonary diseases on mortality in patients with thoracic and/or abdominal aortic aneurysms?
Population
952 patients with TAA, AAA, or TAA + AAA in Japan
Comparison
Presence vs absence of coexisting pulmonary diseases
Design
Retrospective cohort study
Follow-up
Median 4.92 years
Key result
Coexisting lung cancer and idiopathic pulmonary fibrosis were associated with increased mortality among 952 patients with aortic aneurysm, of whom 213 died during a median 4.92-year follow-up.
Authors
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Coexisting LC and IPF linked to higher AA mortality; leaves open whether pulmonary screening alters outcomes.
Cohort (n=952)
No
What is the prognostic impact of coexisting pulmonary diseases on mortality in patients with thoracic and/or abdominal aortic aneurysms?
Coexisting lung cancer and idiopathic pulmonary fibrosis are significant prognostic factors for mortality in patients with aortic aneurysms, independent of age and aneurysm diameter.
Kobayashi et al. (2024) conducted a cohort in Thoracic and/or Abdominal Aortic Aneurysm (n=952). Coexisting pulmonary diseases (lung cancer, idiopathic pulmonary fibrosis) vs. Absence of coexisting pulmonary diseases was evaluated on Mortality. Coexisting lung cancer and idiopathic pulmonary fibrosis were associated with increased mortality among 952 patients with aortic aneurysm, of whom 213 died during a median 4.92-year follow-up.
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