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April 2, 2014Frontiers in PharmacologyOpen Access

Mechanisms of CaMKII Activation in the Heart

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JEJeffrey R. EricksonUniversity of Otago

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Implication

Highlights CaMKII as potential therapeutic target in heart disease; extends mechanistic insights but leaves open clinical validation.

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Cite This Study

Jeffrey R. Erickson (2014) studied this question.

synapsesocial.com/papers/6a7d476801128eec96964d10 https://doi.org/10.3389/fphar.2014.00059

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Oxidized Calmodulin Kinase II Regulates Conduction Following Myocardial Infarction: A Computational Analysis2009 · 71 citations
2Dynamic Kv4.3–CaMKII unit in heart: an intrinsic negative regulator for CaMKII activation2010 · 32 citations
3The δ <sub>C</sub> Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure2003 · 561 citations
4Early apoptosis in different models of cardiac hypertrophy induced by high renin-angiotensin system activity involves CaMKII2012 · 47 citations
5Oxidized CaMKII causes cardiac sinus node dysfunction in mice2011 · 214 citations