Why the study?
Does intensive blood pressure lowering reduce major cardiovascular events compared to standard regimens?
Population
15 trials including a total of 37,348 participants
Comparison
Intensive blood pressure lowering regimens vs Standard blood pressure lowering regimens
Design
Meta-analysis
Authors
Loading...
Supports intensive BP targets in high-risk patients; confirms and quantifies benefits across pooled randomized evidence.
Does intensive blood pressure lowering reduce major cardiovascular events compared to standard regimens?
Intensive blood pressure lowering significantly reduces the risk of major cardiovascular events, stroke, and end-stage kidney disease compared to standard targets, at the cost of increased hypotension.
Lv et al. (2012) studied this question.