What question did this study set out to answer?

February 1, 1991Circulation

Effects of pressure and volume of the receiving chamber on the spatial distribution of regurgitant jets as imaged by color Doppler flow mapping. An in vitro study.

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Why the study?

Does receiving chamber pressure and volume affect the spatial distribution of regurgitant jets imaged by color Doppler flow mapping in an in vitro model?

Population

In vitro constant-flow model with a known orifice (1.5 mm2) and compliant receiving chamber (elastic balloons)

Design

Preclinical

Authors

BMBenedito Carlos MacielUniversidade de Ribeirão Preto VMValdir Ambrósio MoisésUniversidade Federal de São Paulo RSRobin ShandasPediatric Cardiology

Discussion

Member takes

Implication

May bias color Doppler regurgitant jet grading by chamber pressure; leaves open need for pressure-adjusted validation in patients.

Key Points

To evaluate the effects of pressure, volume, and compliance of the receiving chamber on the spatial distribution of regurgitant jets imaged by color Doppler flow mapping.
Designed a steady-flow in vitro model driving fluid through a 1.5 mm² orifice into elastic balloon receiving chambers with varying static compliances (1, 2, 4.5, and 9 ml/mm Hg).
Varied flow rates from 60 to 270 ml/min across compliant chambers held at a constant 150 ml volume (pressures of 57, 28, 18, and 8 mm Hg).
Evaluated different receiving chamber volumes (110, 130, and 150 ml producing pressures of 5, 15, and 24 mm Hg) at a constant static compliance of 2 ml/mm Hg.
Jet area correlated strongly and linearly with jet velocity across the orifice (r = 0.97 to 0.99) and with total flow rate (r = 0.97 to 0.99) across all balloon conditions.
At a constant flow rate and receiving chamber volume, color Doppler jet area decreased as receiving chamber pressure increased (pressures ranging from 8 to 57 mm Hg).

Structured PICO

Does receiving chamber pressure and volume affect the spatial distribution of regurgitant jets imaged by color Doppler flow mapping in an in vitro model?

Population

In vitro constant-flow model with a known orifice (1.5 mm2) and compliant receiving chamber (elastic balloons)

Intervention

Varying flow rates (60 to 270 ml/min) into elastic balloons with different static compliances (1, 2, 4.5, and 9 ml/mm Hg) and volumes (110, 130, and 150 ml)

Outcome

Jet area imaged by color Doppler flow mappingsurrogate

In an in vitro model, the spatial distribution of regurgitant jets assessed by color Doppler is significantly affected by the pressure of the receiving chamber, which may impact clinical evaluation of valvular insufficiency.

Cite This Study

Maciel et al. (1991) studied this question.

synapsesocial.com/papers/6a7d4e14a88f8d6a78a00be1 https://doi.org/10.1161/01.cir.83.2.605

Topics

Valvular heart disease

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Effects of pressure and volume of the receiving chamber on the spatial distribution of regurgitant jets as imaged by color Doppler flow mapping. An in vitro study.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Topics

Effects of pressure and volume of the receiving chamber on the spatial distribution of regurgitant jets as imaged by color Doppler flow mapping. An in vitro study.

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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