Why the study?
Does a 20-week endurance training program modify cardiac dimensions and maximal oxygen uptake in sedentary subjects and monozygotic twins?
Population
40 subjects (20 sedentary subjects and 10 pairs of monozygotic twins)
Comparison
20-week endurance training program vs Baseline (pre-training)
Design
Cohort
Follow-up
20 weeks
Authors
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Genotype may modulate cardiac remodeling and VO2 max gains with endurance training; leaves open causal effects and clinical applicability.
Does a 20-week endurance training program modify cardiac dimensions and maximal oxygen uptake in sedentary subjects and monozygotic twins?
Cardiac dimensions are amenable to significant modifications under controlled endurance training, with the response likely being genotype-dependent.
F. Landry (1985) studied this question.
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