Why the study?
Changes in left ventricular mass and end-diastolic volume in response to exercise training determine functional capacity, but the impact of different exercise modalities remains unclear.
Does endurance training compared to resistance training improve left ventricular mass and end-diastolic volume in previously untrained twins?
Population
72 previously untrained MZ and DZ twin pairs (22 MZ, 14 DZ same-sex pairs; 26.1 ± 5.4 yr)
Comparison
3 months of RES vs 3 months of END training (with 3-month washout)
Design
Randomized crossover trial
Authors
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Endurance training may be prioritized over resistance for LV remodeling in sedentary adults; confirms modality-specific cardiac adaptations.
Does endurance training compared to resistance training improve left ventricular mass and end-diastolic volume in previously untrained twins?
Endurance training, but not resistance training, significantly increases left ventricular mass and end-diastolic volume in previously untrained individuals, with limited genetic impact on adaptation.
Marsh et al. (2022) studied this question.
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