Why the study?
Do new generation antipsychotic drugs cause torsades de pointes in patients with QTc interval prolongation?
Do new generation antipsychotic drugs cause torsades de pointes in patients with QTc interval prolongation?
Current literature does not provide evidence that new generation antipsychotic drugs cause torsades de pointes, suggesting routine ECG monitoring may not be necessary in patients without other risk factors.
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Should not yet change ECG monitoring practices; leaves open whether newer antipsychotics independently increase torsades de pointes risk.
W. Victor R. Vieweg (2003) studied this question.
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