Life’s Crucial 9 Score as a Novel Role for Chronic Obstructive Pulmonary Disease Screening

Purpose: This study aims to investigate the association between the Life's Crucial 9 (LC9) score and chronic obstructive pulmonary disease (COPD) in middle-aged and older adults. Patients and Methods: We screened the NHANES database for data from 2007-2018. Logistic regression analysis and subgroup analysis were used to explore the association between LC9 score and COPD in middle-aged and older adults. Additionally, restricted cubic spline (RCS) was plotted to visually depict the dose-response relationship between the two. Results: A total of 12,030 participants were included, of whom 815 had COPD. After multivariate adjustment, the LC9 score was found to be inversely associated with COPD diagnosis. The RCS visually demonstrated a linear decreasing relationship between the two. Furthermore, subgroup analysis revealed no significant interaction across different subgroups, except for education level. Conclusion: The LC9 score is linearly and inversely associated with COPD diagnosis. Higher LC9 scores are associated with a lower COPD diagnosis in individuals aged 40 and above.