Gender differences in stroke prevention in atrial fibrillation in general practice: using the GRASP-AF audit tool
Why the study?
Does female gender affect the utilization of oral anticoagulation and the risk of stroke or death in patients with atrial fibrillation?
Population
2,259 patients with atrial fibrillation from 11 general practices in Darlington, England, mean age 76, 46%…
Comparison
Female gender vs Male gender
Design
Cohort
Authors
Discussion
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Member takes
Implication
Undertreatment may drive excess stroke risk in women with AF; leaves open whether interventions to equalize OAC use would improve outcomes.
Structured PICO
Does female gender affect the utilization of oral anticoagulation and the risk of stroke or death in patients with atrial fibrillation?
P
Population
2,259 patients with atrial fibrillation from 11 general practices in Darlington, England, mean age 76, 46% female.
I
Intervention
Female gender
C
Comparator
Male gender
O
Outcome
Utilisation of oral anticoagulation (OAC) and prognosis (stroke and all-cause mortality)hard clinical
Women with atrial fibrillation are less likely to receive oral anticoagulation than men despite having a higher baseline risk of stroke, though this risk disparity is eliminated when anticoagulation is prescribed.
Cite This Study
Shantsila et al. (2015) studied this question.