Why the study?
Does a heparin-coated intra-aortic balloon prevent surface clot deposits compared to a standard balloon in a calf model?
Population
Calf model (n=24 intra-aortic balloons total)
Comparison
Heparin-coated intra-aortic balloon (IAB) vs Standard intra-aortic balloon
Design
Preclinical
Follow-up
Up to 6 hours
Authors
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May reduce IAB thrombus in anticoagulation-intolerant patients; leaves open translation from calf model to human outcomes.
Does a heparin-coated intra-aortic balloon prevent surface clot deposits compared to a standard balloon in a calf model?
Heparin-coated intra-aortic balloons completely prevented surface clot deposits in a calf model, suggesting a potential strategy for patients with contraindications to systemic heparinization.
Mueller et al. (1999) studied this question.
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