Why the study?
Does enoxaparin improve fetal outcomes and prevent thromboembolic complications compared to warfarin in pregnant women with mechanical heart valves?
Population
31 pregnant women with mechanical heart valves attending high-risk antenatal clinics.
Comparison
Enoxaparin predominantly used during pregnancy. vs Primarily warfarin, with enoxaparin given in the…
Design
Cohort
Follow-up
Through pregnancy and postpartum
Authors
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May support enoxaparin preference for fetal survival in mechanical valve pregnancies; leaves open need for randomized confirmation.
Does enoxaparin improve fetal outcomes and prevent thromboembolic complications compared to warfarin in pregnant women with mechanical heart valves?
Therapeutic dose enoxaparin during pregnancy in women with mechanical heart valves is associated with good fetal outcomes and a low risk of valve thrombosis, provided there is strict compliance and close monitoring of anti-Xa levels.
McLintock et al. (2009) studied this question.
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