Why the study?
Does 1.6 mL/kg of 7.5% hypertonic saline prevent hypotension as effectively as 13 mL/kg of 0.9% normal saline before spinal anesthesia in patients undergoing lower limb surgery?
Does 1.6 mL/kg of 7.5% hypertonic saline prevent hypotension as effectively as 13 mL/kg of 0.9% normal saline before spinal anesthesia in patients undergoing lower limb surgery?
Hypertonic saline (7.5%) is as effective as normal saline (0.9%) for initial fluid administration before spinal anesthesia, achieving hemodynamic stability without excess free water administration.
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Supports hypertonic saline as volume-sparing prehydration before spinal anesthesia; confirms hemodynamic equivalence to normal saline.
Järvelä et al. (2000) studied this question.
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