Key result
Hypertonic saline (3%) preload was more effective than normal saline (0.9%) in preventing spinal-induced hypotension during cesarean section, without affecting neonatal outcomes.
Why the study?
Does hypertonic saline (3%) prevent spinal induced hypotension better than normal saline (0.9%) in parturient patients undergoing cesarean section?
RCT (n=40)
Randomized
Does hypertonic saline (3%) prevent spinal induced hypotension better than normal saline (0.9%) in parturient patients undergoing cesarean section?
Hypertonic saline (3%) preload is more effective than normal saline (0.9%) in preventing spinal-induced hypotension during cesarean section without adverse neonatal effects.
Spinal anesthesia-induced hypotension in cesarean delivery requires proactive management; leaves open optimal prevention protocols in emergency settings.
Background: spinal anesthesia is frequently used for cesarean delivery because of its rapid onset, a dense neural block, little risk of local anesthetic toxicity and minimal transfer of drug to the fetus. General anesthesia is preferred in emergency obstetric situations, such as cord prolapse, in which there is a need for reliable induction, and also bleeding placenta previa. Unfortunately it is frequently accompanied by hypotension, which may be defined in absolute terms as a systolic blood pressure (SBP) of 90 or 100 mmHg or in relative terms as a percentage (20% fall from baseline). Aim of the Work: the aim of this study is to compare hypertonic saline (3%)and normal saline (0.9%) in preventing spinal induced hypotension. Patients and Methods: in our study, 40 patients were randomly divided into 2 equal groups: Group A: received hypertonic saline (3%) (4ml/kg) . Group B: received normal saline (0.9%)(13ml/kg). Results: our study showed that hypertonic saline (3%) was more effective than normal saline to prevent spinal induced hypotension and it did not affect the neonatal outcome. Conclusion: neonatal outcome was excellent with the use of either hypertonic saline (3%) or normal saline (0.9%) as a preload for the parturient who received spinal anesthesia before cesarean section.
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Latif et al. (2018) conducted an RCT in Spinal-induced hypotension during cesarean section (n=40). Hypertonic saline (3%) vs. Normal saline (0.9%) (13ml/kg) was evaluated on Spinal induced hypotension. Hypertonic saline (3%) preload was more effective than normal saline (0.9%) in preventing spinal-induced hypotension during cesarean section, without affecting neonatal outcomes.
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