What does this research mean for the field?

Worse social determinants of health are independently associated with higher cardiovascular, cancer, and all-cause mortality among cancer survivors, but not among individuals without cancer. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the cause-specific mortality risks associated with social determinants of health among cancer survivors compared to individuals without a cancer history.

October 30, 2024European Journal of Preventive CardiologyOpen Access

Associations between social determinants of health and cardiovascular and cancer mortality in cancer survivors: a prospective cohort study

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Cancer survivors (n=37882). Intervention: Worse social determinants of health (SDOH) vs. Better social determinants of health. Primary outcome: Cardiovascular mortality (aHR 1.31, 95% CI 1.02-1.68).

View Full Paper

Ask AI

Bookmark

Key result

Worse social determinants of health linked to ~31% higher CV mortality in cancer survivors.

aHR 1.31
95% CI 1.02-1.68
n=37,882

Why the study?

Are worse social determinants of health associated with increased cardiovascular and cancer mortality in cancer survivors?

Key Points

To evaluate the cause-specific mortality risks associated with social determinants of health among cancer survivors compared to individuals without a cancer history.
Prospective cohort study analyzing 37,882 participants (4,179 cancer survivors and 33,703 individuals without cancer) from the 2013–2017 National Health Interview Survey.
Social determinants of health were evaluated using a 38-point, 6-domain deprivation score, with primary cardiovascular mortality and secondary cancer and all-cause mortality analyzed via cause-specific multivariable Cox regression.
Among cancer survivors, worse social determinants of health scores were significantly associated with increased cardiovascular mortality (aHR 1.31, 95% CI 1.02–1.68), cancer mortality (aHR 1.20, 95% CI 1.01–1.42), and all-cause mortality (aHR 1.16, 95% CI 1.02–1.31) after adjustment for demographics, comorbidities, and risk factors.
Among individuals without cancer, social determinants of health showed no independent association with cardiovascular or all-cause mortality after controlling for comorbidities and risk factors, with no association detected for cancer mortality.

Study Design

Type

Cohort (n=37,882)

Structured PICO

Are worse social determinants of health associated with increased cardiovascular and cancer mortality in cancer survivors?

Population

37,882 individuals, including 4,179 cancer survivors and 33,703 individuals without cancer, from the 2013 to 2017 National Health Interview Survey.

Exposure

Worse social determinants of health (SDOH), quantified using a 38-point, 6-domain score

Comparator

Better social determinants of health (lower SDOH score)

Outcome

Cardiovascular mortalityhard clinical

Main Result

Hazard Ratio: 1.31 (95% CI 1.02–1.68)

Discussion

No takes yet. Share an insight, caveat, or question.

Implication

Social determinants of health are independently associated with cardiovascular, cancer, and all-cause mortality in cancer survivors, highlighting the need to address social deprivation in cardio-oncology care.

Cite This Study

Chan et al. (2024) conducted a cohort in Cancer survivors (n=37,882). Worse social determinants of health (SDOH) vs. Better social determinants of health was evaluated on Cardiovascular mortality (aHR 1.31, 95% CI 1.02-1.68). Among cancer survivors, worse social determinants of health were associated with higher cardiovascular mortality (aHR 1.31; 95% CI 1.02-1.68).

synapsesocial.com/papers/6a7d69f1c7e6f6a50737d8c4 https://doi.org/10.1093/eurjpc/zwae318

View Full Paper

Ask AI

Bookmark

Associations between social determinants of health and cardiovascular and cancer mortality in cancer survivors: a prospective cohort study

Key Points

Study Design

Structured PICO

Main Result

Discussion

Implication

Cite This Study

Associations between social determinants of health and cardiovascular and cancer mortality in cancer survivors: a prospective cohort study

Key Points

Study Design

Structured PICO

Main Result

Discussion

Implication

Cite This Study

Also Consider

Also Consider